Teaching chemistry and mathematics at the secondary level aims to build a solid scientific foundation and develop analytical thinking by connecting shared concepts. Chemistry content includes topics such as atomic structure, reactions, and organic chemistry, while mathematics covers algebra, functions, and calculus. Integration is demonstrated by using algebraic equations to balance reactions, logarithms to calculate pH, and differential calculus to study reaction rates. Effective teaching methods rely on discovery learning, computer simulations, and practical projects that integrate the two subjects. Challenges such as the difficulty of abstraction, individual differences, and time constraints necessitate comprehensive planning by the teacher, varied assessment methods, the stimulation of scientific curiosity, and continuous professional development.