Introduction to Genetics and genetic studies. Mendel's experiment and laws of genetics

With the Genetics course, an undergraduate student will be exposed to a clear, comprehensive, and balanced introduction to genetics and genomics. The material deals with transmission genetics and molecular genetics, as fully integrated subjects, and provides an understanding of the basic processes of gene transmission, mutation, expression, and regulation.

Upon successful completion of the course, students must be able to:

Common outcomes:

a - Solve genetic problems of several types.

b - Write and State genetic principles in their own words and recognize the key terms of genetics in context.

c - Be able to think like a geneticist at the elementary level of being able to formulate genetic hypotheses, work out their consequences, and test the results against observed data.

d - Gain some sense of the social and historical context in which genetics and genomics has developed and is continuing to develop.

e - Develop critical thinking and analytical skills.

Specific Outcomes:
1.1 - Analyze a pedigree, determine the mode of inheritance and genotypes, and predict offspring ratios.
1.2 - Inspect data from 3-point mapping crosses.
1.3 - Test the goodness-of-fit of experimental data to theoretical predictions using the chi-squared test.
2.1 – Discover and discuss the basic processes of gene transmission, mutation and expression.

2.2 - Assess the principal experimental methods that geneticists use in their studies, and consider the advantages and limitations of these approaches.

2.3 - Investigate the modes of gene expression regulation.

3.1 – Examine the role of every component of eukaryotic and prokaryotic chromosomes.

3.2 – Predict and evaluate the consequences of genomic rearrangements.

3.3 – Analyze genome organization and the parameters affecting DNA renaturation.

4.1 – Consider the different mechanisms of genetic exchanges.

4.2 – Practice how transformation, transduction and conjugation can be used in gene

With the Molecular Biology course, the student will acquire knowledge in the field of modern molecular biology as it covers the molecular mechanisms of gene expression and regulation, the fundamental aspects of recombinant DNA technology, the protein structure and function, the signaling pathways that control gene activity, the regulation of the eukaryotic cell cycle, the Cell birth lineage and death, and Cancer.

Course Learning Outcomes:

Upon successful completion of the course, students must be able to:

Common outcomes:

a - Identify and discuss several molecular mechanisms underlying cellular functions.

b – Solve molecular problems of several types.

c - Develop critical thinking and analytical skills in molecular biology research.

d – Develop scientific communication.

Specific Outcomes:

1.1- Inspect and contrast the genetic engineering methods that molecular biologists use in their studies in order to determine gene function, and discriminate the advantages and limitations of these approaches.

1.2- Analyze and evaluate the applications of recombinant DNA technology.

2.1- Practice a genome-wide analysis of gene structure and expression.

2.2- Identify the transcriptional and post transcriptional gene expression regulation.

2.3- Acquire knowledge about the histone code and dissect how chromatin remodeling plays an important role in the determination of gene expression pattern.

2.4- Investigate how the post translational modifications participate in regulating gene function.

3.1- Consider biology at new levels of complexity, such as large multiprotein signaling complexes in cells.

3.2- Interpret how signaling pathways control gene activity.

4.1- Examine the molecular aspects underlying the activation of the origins of replication and the occurrence of the early and late mitotic events.